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Cushing's Disease

Cushing’s disease, or Pituitary Pars Intermedia Dysfunction (PPID) is a chronic, progressive condition caused by an imbalance in the hormones produced by the pituitary gland. The disease commonly affects horses and ponies over the age of 15 and due to rising life expectancy rates, it is becoming increasingly prevalent. 

Clinical Signs

Signs can often vary from horse to horse and some may be more obvious than others. They often include:

  • Muscle wastage 
  • Abnormal fat deposits and sweating
  • Reduced immune function; this can result in recurring skin and respiratory infections including sinusitis, dental disease and an increased susceptibility to worms.
  • Lethargy
  • Laminitis 
  • Increased thirst and urination
  • Abnormal coat

It is important to contact your vet if you believe your horse is suffering from Cushing’s


Early diagnosis of horses and ponies affected by Cushing’s gives the chance for management strategies to be implemented to deliver the best outcome. However, the initial stages of the condition are often slow to appear, can be difficult to detect and are sometimes overlooked, which may result in a delay before diagnosis and management of the disease. 

A blood test is needed to confirm the diagnosis which can be carried out by your vet.


Although Cushing’s is incurable, management strategies can be implemented and medication may be advised to help normalise the hormone secretion and reduce the signs associated with the disease. 


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